Celox (chitosan) for haemostasis in massive traumatic bleeding: experience in Afghanistan.
نویسندگان
چکیده
The use of Celox, a chitosan-based haemostatic agent, for the control of massive traumatic bleeding in patients arriving at a ROLE 2 (Enhanced Care) Facility in southwestern Afghanistan is described. Twenty-one soldiers with gunshot wounds were treated with successful haemostasis in 18 at the first application and in three after further applications. Celox is an effective haemostatic agent and a useful adjunct for the treatment of massive traumatic bleeding.
منابع مشابه
Effects of Celox and TraumaDEX on hemorrhage control in a porcine model.
The purpose of this study was to compare the effectiveness of 2 hemostatic agents, chitosan-based Celox and the biopolymeric, microporous particles TraumaDEX, with a control group in a porcine model of hemorrhage. The animals were randomly assigned to 1 of 3 groups: Celox (n = 5), TraumaDEX (n = 5), or a standard pressure dressing alone (n = 5). To simulate a battlefield injury, the investigato...
متن کاملA new hemostatic agent: initial life-saving experience with Celox (chitosan) in cardiothoracic surgery.
Celox (MedTrade Products Ltd, Cheshire, UK) is a proprietary preparation of chitosan, indicated for moderate to severe hemorrhage and currently used for hemostasis in the emergency and military settings. We describe its lifesaving use in 2 patients undergoing cardiothoracic surgery in which conventional techniques had failed.
متن کاملHemostatic effect of a chitosan linear polymer (Celox®) in a severe femoral artery bleeding rat model under hypothermia or warfarin therapy.
BACKGROUND In this study, the hemostatic efficacy of Celox® in rats under hypothermia or warfarin treatment was investigated. METHODS A total of forty-eight Sprague-Dawley female rats weighing 200-350 g were used in the study. Six experimental study groups were designed, as follows: Group 1: Normothermia + compression; Group 2: normothermia + Celox®; Group 3: hypothermia + compression; Group ...
متن کاملComparison of the Efficiencies of Buffers Containing Ankaferd and Chitosan on Hemostasis in an Experimental Rat Model with Femoral Artery Bleeding
OBJECTIVE In the first assessment of trauma patients with major vascular injuries, we need effective and rapid-acting homeostatic materials. In this study we compare the efficiencies of Ankaferd Blood Stopper® and a chitosan linear polymer (Celox®) in an experimental rat model with femoral artery bleeding. MATERIALS AND METHODS Thirty male Wistar albino rats weighing 200-250 g were divided in...
متن کاملComparison of 10 hemostatic dressings in a groin puncture model in swine.
BACKGROUND The use of mineral (clay) or biologic (chitosan) materials has improved the efficacy of dressings used in the bleeding control of noncompressible areas. A series of novel manufactured products already evaluated in a vascular transection model was further compared in a severe vascular puncture injury model. METHODS Ten hemostatic dressings were tested in anesthetized Yorkshire swine...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- European journal of emergency medicine : official journal of the European Society for Emergency Medicine
دوره 18 1 شماره
صفحات -
تاریخ انتشار 2011